PE-22-28 10mg

PE-22-28 is a synthetic peptide derived from spadin, which itself originates from the protein sortilin found in the central nervous system. This shortened sequence appears to interact with the TREK-1 potassium channel, a receptor linked to mood regulation, memory, and cognitive function. Research suggests that modulating TREK-1 activity may influence neuronal excitability and has been explored in models of depression. Beyond mood-related studies, TREK-1 is also of interest in research on anesthesia, pain sensitivity, and neuroprotection.