Ipamorelin 10mg
$80.00
Quantity: | 10mg |
---|---|
Unit: | 1 vial |
Contents: | Ipamorelin |
Form/Appearance: | Lyophilized/Powder |
Peptide Purity: | 99% |
Sequence: | Aib-His-D-2Nal-D-Phe-Lys |
Molecular Mass: | 711.87 g/mol |
Solubility: | Sterile / Bacteriostatic water |
Synonyms: | NNC 26-0161 |
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Oxytocin, also known as the love hormone, helps us bond with our loved ones and is often released through touch, exercise, and music.
What is Oxytocin?
This natural hormone manages crucial aspects of male and female reproductive systems, including lactation, labor, delivery, and certain aspects of human behavior. The hypothalamus produces oxytocin, but the posterior pituitary gland releases and stores this hormone into the bloodstream.
Hormones are chemicals that manage various functions in the human body by carrying messages through blood to tissues, muscles, and organs. These signals instruct your body what to do and when to do it.
The hypothalamus is part of the brain that controls functions such as heart rate, digestion, body temperature, and blood pressure. On the other hand, the pituitary gland is a small, pea-sized endocrine gland placed at the base of the brain, below the hypothalamus.
Synthetic Forms of Oxytocin
A synthetic form of oxytocin is used in hospital settings, particularly when doctors need to induce labor in childbirth if it hasn’t begun naturally or to help with contractions. Healthcare providers may also use this hormone to speed up the delivery of the placenta, which is the third stage of labor, and minimize the risk of heavy bleeding.
Function of Oxytocin
As previously mentioned, the two main functions of oxytocin are to encourage uterine contractions in childbirth and labor and to boost contractions of breast tissue to help with lactation after childbirth.
However, apart from these, oxytocin has other important roles, such as:
- Placenta-infant bonding
- Romantic attachment
- Trust
- Recognition
- Sexual arousal
The effects of oxytocin on the human brain are complex, and scientists are currently researching the role of oxytocin in various conditions.
- PTSD
- Depression
- Autism spectrum disorder
- Anxiety
- Anorexia
- Addiction
Florea T, Palimariciuc M, Cristofor AC, Dobrin I, Chiriță R, Bîrsan M, Dobrin RP, Pădurariu M. Oxytocin: Narrative Expert Review of Current Perspectives on the Relationship with Other Neurotransmitters and the Impact on the Main Psychiatric Disorders. Medicina (Kaunas). 2022 Jul 11;58(7):923. doi: 10.3390/medicina58070923. PMID: 35888641; PMCID: PMC9318841.
Kendrick KM, Guastella AJ, Becker B. Overview of Human Oxytocin Research. Curr Top Behav Neurosci. 2018;35:321-348. doi: 10.1007/7854_2017_19. PMID: 28864976.
https://www.sciencedirect.com/science/article/pii/S0306453013002369
Epitalon is a synthetic peptide, made up of 4 amino acids – alanine, glycine, glutamic and aspartic acid. It’s based on a natural peptide epithalamion, commonly extracted from the pineal gland. Some earlier studies showed epitalon’s antioxidant potential, so more recent ones started focusing on its anti-aging potential.
Recent studies also showed its potential in regulating DNA changes, treating infectious diseases… even addressing some types of cancer.
Anti Aging Properties
The fact that epitalon is epithalamin’s extract, means it has the ability to eliminate free radicals that cause tissue damage. A particular research study on flies and mice showed that, after epitalon’s administration, fruit flies mortality rate dropped by a whopping 52%, while the mortality rate in rats dropped by 27%, as compared to the control studies. What researchers learned from this study was that regular epitalon administration stimulated the synthesis and secretion of melatonin, which inhibits free radical production and its subsequent damage.
There was another in vitro study on human somatic non-reproductive cells suggesting that epitalon peptide affects telomerase activity. Telomerase is an enzyme present in cells, allowing them to live longer. So, essentially, this study showed the researchers that this therapy leads to the prolonged cell lifespan. Of course, we still need full scale human studies to see the full extent of prolonged cell lifespan.
DNA Effects
Epitalon also interacts with DNA gene expression, allowing it to have an indirect effect on a whole host of potential bodily functions – from immune system, to skin, tendon and connective tissue repair.
This essentially allows epitalon peptide therapy to have a dual potential effect – on the one hand, it strengthens the immune system and protects the body from outside factors, and on the other, it allows the body to repair and regenerate its structures on its own.
Skin Cell Regeneration
We already talked about epitalon’s effect on DNA and genes. This effect extends to the fibroblast producing and maintaining MMP2. Interestingly, this peptide also affects other skin components, such as collagen and elastin.
Of course, we still have yet to see definitive human studies, but animal ones showed promising results. Young and old rats exposed to epitalon showed skin fibroblast proliferation of 29 and up to 45%. Not only that, epitalon also activates enzymes that slow down programmed cell death.
References:
Yue X, Liu SL, Guo JN, Meng TG, Zhang XR, Li HX, Song CY, Wang ZB, Schatten H, Sun QY, Guo XP. Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro. Aging (Albany NY). 2022 Apr 12;14(7):3191-3202. doi: 10.18632/aging.204007. Epub 2022 Apr 12. PMID: 35413689; PMCID: PMC9037278.
Anisimov VN, Mylnikov SV, Khavinson VK. Pineal peptide preparation epithalamin increases the lifespan of fruit flies, mice and rats. Mech Ageing Dev. 1998 Jun 15;103(2):123-32. doi: 10.1016/s0047-6374(98)00034-7. PMID: 9701766.
Khavinson VKh, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003 Jun;135(6):590-2. doi: 10.1023/a:1025493705728. PMID: 12937682.
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