FOX04-DRI 10mg (Proxofim)

FOXO4-DRI (Retro-Inverso) is a lab-engineered variant of the natural FOXO4 protein, designed with slight modifications that extend its stability in the body. These changes enable it to disrupt the normal interaction between FOXO4 and p53. By preventing this binding, research suggests FOXO4-DRI can help clear senescent cells, support healthier organ performance, and promote tissue that functions more like that of a younger biological age. It has been associated with influencing insulin pathways, cell cycle control, and responses to oxidative stress. As a cell-penetrating peptide, FOXO4-DRI has demonstrated the ability in animal studies to trigger selective apoptosis in senescent cells, potentially counteracting some age-related effects.